The most commonly applied infertility treatment for couples who cannot have children naturally is IVF treatment. The first birth as a result of IVF treatment took place in 1978. Since then, many changes have taken place in the treatment process and a lot of progress has been made. Despite all these developments, it is not possible to talk about 100% success rate for IVF treatment. Multiple trials may be required for IVF treatment, and this requirement may become an experience that challenges couples in various ways. Therefore, evaluating the possibilities at the very beginning of the process can have a significant impact on the success rate of IVF treatment.
Failure to take precautions against some factors that lead to the need for IVF treatment, may reduce the success rate of IVF treatment. Take fallopian tube problems, for example. In order for pregnancy to occur naturally, at least one of the tubes must be open and structurally sound.
Any obstruction in the tubes and the accumulation of fluid in the tubes is called hydrosalpinx. In the presence of hydrosalpinx, leakage of fluid accumulated in the tube into the uterus may interfere with embryo transfer. So, if the cause of infertility is hydrosalpinx, at first, this health problem should be addressed.1
There is a linear correlation between the success rate of IVF treatment and the embryo quality. With the developing technology, the highest quality embryos can be selected and healthy birth rates can be increased for the couples with risk of genetic diseases. Preimplantation genetic testing can be briefly defined as a technique that allows the identification of genetic defects in embryos formed through IVF.2
If a genetic anomaly is present in one or both parents, this diagnostic method, which makes it possible to select the healthiest embryo among the embryos formed, has an important effect on increasing the success rate of IVF. PGT can also be recommended when there is no risk of genetic diseases. In recurrent IVF failures, severe male infertility, unexplained infertility, and late age of the expectant mothers, PGT can increase the success rate of IVF.
Although IVF treatment basically consists of the stages of stimulation of ovaries, collection of egg and sperm cells, fertilization and embryo transfer, it also includes many auxiliary methods performed to support these stages.
The main purpose of auxiliary methods is to increase the success rate of IVF treatment. Therefore, it is decided whether they will be applied in accordance with the couple in question. For more detailed information about Auxiliary Methods in IVF Treatment, you can access the relevant page via this link. To mention briefly, thanks to the auxiliary methods such as ICSI3, which is included in the process in cases where sperm quality is low, PRP application to the ovaries to increase egg quality, and endometrial scratching to facilitate embryo transfer, solutions can be found to "couple-specific" problems that are likely to reduce the success rate of IVF treatment.
The advances in medical technologies, the development of treatment processes significantly increase the success rates of IVF. However, the fact that couples have important duties in this process should not be ignored. It is very important to abandon bad habits that harm sperm and egg quality months before IVF treatment begins.
It is known that habits such as smoking and alcohol consumption, being overweight, stress, an unhealthy diet and inactivity can have a negative effect on the success rate of IVF treatment. Therefore, couples who decide to resort to infertility treatments to have a baby need to take the necessary steps to live a healthier life.
Stress after infertility diagnosis is extremely common and there are many scientific studies showing that infertility leads to stress. The controversial and generally accepted fact, although not yet certain, is that stress can be a cause of infertility. Some studies conducted in recent years have shown that for women with high levels of the alpha-amylase enzyme in their saliva, which indicates stress, it take 29% longer to conceive compared to women who have low levels of this enzyme. We also know that cortisol, known as the stress hormone, affects the signaling between the brain and the ovaries.4 Therefore, success in stress management remains an important factor in the process of IVF treatment. In order to eliminate the stress and concerns experienced specifically during the period, couples may want to receive psychological support.
1 https://pubmed.ncbi.nlm.nih.gov/25436898/
2 https://emedicine.medscape.com/article/273415-overview
3 https://www.ucsfhealth.org/education/faq-intracytoplasmic-sperm-injection
4 https://www.webmd.com/baby/features/infertility-stress
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