The creation of quality embryos by fertilizing quality eggs with quality sperms can increase the success of IVF treatment. One of the auxiliary methods that can be applied to increase the success rate of IVF treatment is the microchip method. One of the distinguishing features of the microchip method is that it increases the likelihood of a sperm with healthy DNA can be selected.
In the microchip method, in order to create quality embryos, it is aimed to select sperms that are in correct shape, motile and have a healthy DNA structure, with the help of microfluidic technology. In the microchip method, selection is carried out in a natural way. The microchip method, in which a separation process is applied that mimics the natural bodily functions, may also be used in intrauterine insemination treatment as well as in IVF treatment.
In the microchip technique, which is performed to select motile sperms with quality DNA for embryo formation, the sperm fluid taken from the male is dripped onto a chip with microchannels narrower than half a millimeter. Among the sperms injected into the chip, only healthy and viable ones come out of the channel. Thus, damaged and poor quality sperm and healthy ones are separated from each other.
In sperm selection with microchip technology, it can be said that sperm cells are competing in a sense. During the race, they pass through microchannels in a solution that simulates the natural environment. Those who successfully complete this process and come to the finish line are the healthy ones. In other words, the ones who are most likely to fertilize the egg will be the ones who finish the race first.
The selection of quality and healthy sperms is extremely important in terms of increasing the success of IVF treatment. The microchip method ensures that healthy and unhealthy sperms are separated in a natural way and there is no damage to the structure of the sperm in this process.
Thanks to this method, high-quality embryos can be created. High embryo quality can seriously increase the chances of implantation and pregnancy. Apart from all these, the reduced possibility of miscarriage is among the advantages of the microchip method.
Microchip method is one of the prominent techniques in cases of male-induced infertility, unexplained infertility and recurrent IVF failures. In recent years, sperm selection techniques for ICSI are developing at a rapid pace. It is possible to select the best sperm with different techniques in different patient groups. Apart from microchip method, PICSI, IMSI and MACS methods are also among the most preferred sperm selection methods.
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